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Correspondence
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Volume 347:854-855 September 12, 2002 Number 11
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Germ-Line Mutations in Nonsyndromic Pheochromocytoma

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by Neumann, H. P.H.
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To the Editor: The article on germ-line mutations in nonsyndromic pheochromocytoma, by Neumann et al. (May 9 issue),1 contains a common point of confusion: the terms "paraganglioma" and "glomus tumor" are used interchangeably. They are not interchangeable. The glomus tumor is a tumor of modified perivascular smooth muscle, which frequently presents as a painful subungual mass, and is unrelated to tumors of the adrenal and extraadrenal paraganglia. The tumor to which the authors are actually referring is the jugulotympanic paraganglioma, which has been mistakenly referred to as a "glomus jugulare tumor" in the past. This neoplasm, which was recognized as . . . [Full Text of this Article]



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