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Previous Volume 347:1094-1103 October 3, 2002 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Treatment of pain and suffering should be a priority for all clinicians. Previous reviews¹ decried inadequate treatment of pain in infants and children. Surveys in the 1970s and 1980s² reported that infants and children were less likely to receive postoperative analgesics than adults. In that era, some neonates underwent surgery with minimal anesthesia,³ although this practice received some criticism.⁴

Studies over the past 15 years suggest that neonates, infants, and children can receive analgesia and anesthesia safely, with proper age-related adjustments in clinical practice and dosing. Although the emphasis in this review is on the pharmacologic management of pain, several . . . [Full Text of this Article]

Development of Nociception

Developmental Issues in Pain Assessment and Measurement

General Aspects of Developmental Pharmacology

Acetaminophen, Aspirin, and Nonsteroidal Antiinflammatory Drugs

Opioids

Pharmacokinetics of Opioids in Neonates, Infants, and Children

Opioid Pharmacodynamics and Clinical Outcomes in Neonates, Infants, and Children

Patient-Controlled Analgesia in Children

Local Anesthetics

General Anesthesia for Neonates and Infants

Treatment of Pain Due to Cancer

Pharmacologic Management of Chronic Noncancer Pain

Source Information

From the Departments of Anesthesia (C.B.B., N.F.S.) and Medicine (C.B.B.), Children's Hospital; and the Departments of Anesthesia (C.B.B., N.F.S.) and Pediatrics (C.B.B.), Harvard Medical School — both in Boston.

Address reprint requests to Dr. Berde at the Pain Treatment Service, Children's Hospital, 333 Longwood Ave., Rm. 555, Boston, MA 02115.

Related Letters:

Analgesics for the Treatment of Pain in Children
Birenbaum D., Mattison D. R., Berde C., Sethna N.
Extract | Full Text | PDF  
N Engl J Med 2003; 348:959-960, Mar 6, 2003. Correspondence

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