Treatment of hypertension in patients with normal renal functiondoes not generally cause renal dysfunction. By contrast, inpatients with hypertension and chronic renal insufficiency,it is not uncommon for the serum creatinine concentration torise as the blood pressure is lowered. This complication islikely to be encountered more often since the guidelines governingadequate blood-pressure control have been made more stringent.1,2For many physicians, the initial response to a deteriorationin renal function is to decrease the dose of antihypertensivemedications. This approach is based on the belief that the kidneyhas been affected by an adverse event . . . [Full Text of this Article]
Renal Autoregulation
Renal Autoregulation in Chronic Hypertension
Renal Dysfunction and Specific Antihypertensive Drugs
ACE Inhibitors
Angiotensin-Receptor Blockers
Diuretics
Calcium-Channel Blockers
Beta-Blockers and Other Classes of Antihypertensive Drugs
Hyperkalemia as a Complication of Antihypertensive Therapy
Source Information
From the Department of Medicine, Division of Nephrology, University of Texas Southwestern Medical School, Dallas.
Address reprint requests to Dr. Palmer at the Department of Medicine, Division of Nephrology, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX 75390-8856, or at biff.palmer@utsouthwestern.edu.
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