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Volume 347:1306-1307 October 24, 2002 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the late 1950s, two sets of observations led to the recognition of a new cardiac disease. One was the discovery, by cardiovascular surgeons and cardiologists, of patients with subaortic pressure gradients at cardiac catheterization but without evidence of anatomical obstruction at surgery. These patients' hearts were also markedly hypertrophied. Simultaneously, pathologists and cardiologists described families in which several members had died suddenly and unexpectedly and were found to have hypertrophied hearts at autopsy. These seemingly unrelated observations rapidly came together and led to the delineation of what is now called hypertrophic cardiomyopathy. This condition has captured the attention and . . . [Full Text of this Article]

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