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Previous Volume 347:1535-1536 November 7, 2002 Number 19 Next

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To the Editor: Allergy to peanuts is potentially fatal, affects 1 in 150 persons in the United States, and until recently was considered to be permanent.^1,2 However, recent reports document a 20 percent rate of resolution by school age.^3,4 We offer an institutionally approved research protocol for double-blind, placebo-controlled oral food challenges for use in children older than 3.5 years of age who have been allergic to peanuts and who have a clinical profile consistent with potential resolution of peanut allergy, as defined by the absence of recent reactions and a serum peanut-specific IgE antibody concentration of less than 10 . . . [Full Text of this Article]

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