To the Editor: Two reports in the Journal1,2 have suggestedthat patients who have psychopathologic symptoms before beginninginterferon alfa therapy may have more severe adverse psychiatriceffects in response to treatment. This suggestion was basedon the observation that patients' scores on psychopathologicrating scales before interferon alfa therapy were positivelycorrelated with the scores after four weeks of treatment.1,2However, we and others have found that patients with a psychiatricdiagnosis can successfully complete interferon alfa therapy.3,4An editorial in the Journal has rightly emphasized that withholdinginterferon alfa inappropriately, especially from members ofa stigmatized class, "raises . . . [Full Text of this Article]
Pariante, C. M.
(2006). The glucocorticoid receptor: part of the solution or part of the problem?. J Psychopharmacol
20: 79-84
[Abstract]
Maddock, C., Baita, A., Orru, M. G., Sitzia, R., Costa, A., Muntoni, E., Farci, M. G., Carpiniello, B., Pariante, C. M.
(2004). Psychopharmacological Treatment of Depression, Anxiety, Irritability and Insomnia in Patients Receiving Interferon-{alpha}: a Prospective Case Series and a Discussion of Biological Mechanisms. J Psychopharmacol
18: 41-46
[Abstract]
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