FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 347:1724 November 21, 2002 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article PubMed Citation

To the Editor: In his letter to the editor, Kaplan (July 18 issue)¹ suggests that cetirizine is one of the active ingredients of hydroxyzine. It is not, although their chemical structures are similar.

Stanley Scheindlin, D.Sc.
3011 Nesper St.
Philadelphia, PA 19152

1. Kaplan AP. Chronic urticaria and angioedema. N Engl J Med 2002;347:222-222. [Free Full Text]

To the Editor: My statement regarding the relation of cetirizine to hydroxyzine warrants clarification. Cetirizine is the active metabolite (not ingredient) of hydroxyzine, and as such, cetirizine is responsible for much of the histamine H₁–receptor blockade associated with the use of hydroxyzine, even though hydroxyzine has H₁-receptor–binding activity in vitro.

Allen P. Kaplan, . . . [Full Text of this Article]

Related Letters:

Prophylaxis against Venous Thromboembolism after Surgery for Cancer
Moulias S., Bouchon J.-P., Meaume S., Bergqvist D., the ENOXACAN II Study Group
Extract | Full Text | PDF  
N Engl J Med 2002; 347:220, Jul 18, 2002. Correspondence

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.