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Book Review
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Volume 347:1898-1899 December 5, 2002 Number 23
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Hormone Replacement Therapy and Cancer: The Current Status of Research and Practice

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(Controversial Issues in Climacteric Medicine Series.) Edited by Andrea R. Genazzani. 281 pp., illustrated. New York, Parthenon, 2002. $79.95. ISBN 1-84214-079-5.

A book that promises to summarize "the current status of research and practice" by its nature always falls short of the mark. There is no better example of such a book than this one on hormone-replacement therapy and cancer. Long-held notions about the benefits of hormone-replacement therapy were recently dispelled with the publication in the Journal of the American Medical Association of the first large randomized, placebo-controlled trial of conjugated equine estrogen plus medroxyprogesterone acetate in healthy women. Contrary to the results of previous case–control and cohort studies showing reduced rates of cardiovascular disease in women receiving hormone-replacement therapy, the . . . [Full Text of this Article]



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