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Previous Volume 347:1968-1970 December 12, 2002 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Loss of vision caused by apoptotic cell death is a feature of age-related macular degeneration, retinitis pigmentosa, glaucoma, and other degenerative retinal diseases. Degeneration of photoreceptors — cells that transduce the light — is involved in macular degeneration and retinitis pigmentosa, whereas loss of retinal ganglion cells, the output neurons of the retina that project through the optic nerve, results in glaucoma.

It has long been known that exposure to intense light causes the degeneration and death of photoreceptors. Recently, Grimm et al.¹ used mouse models of photochemical retinal injury to decipher the process of apoptosis in photoreceptor cells. They . . . [Full Text of this Article]

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