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Editorial
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Volume 347:280-281 July 25, 2002 Number 4
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Prevention of Neonatal Group B Streptococcal Infection

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 by Schrag, S. J.
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The highest annual death rate before the sixth decade of life occurs during the first year of life.1 Most deaths during the first year occur during the perinatal period, particularly between the onset of labor and 72 hours after birth. Infection, often acquired before birth, is one explanation. Because neonates have an immune response to microbes that is depressed relative to those of older children and adults, they have an increased risk of infection-related illness and death. Group B streptococci and Escherichia coli cause most cases of sepsis in neonates.

Well-established risk factors for early-onset group B streptococcal sepsis (that . . . [Full Text of this Article]


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