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Volume 347:462-463 August 15, 2002 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Eons ago, a retrovirus hijacked a gene from a chicken cell and enclosed it within its own genome. The captured gene was not idle, however: it gave the renegade virus the ability to cause tumors in chickens with amazing rapidity. The virus is the Rous sarcoma virus, the gene in the virus is called v-src, and the cellular gene is c-src. These discoveries shifted the tectonic plates of cancer research, thereby opening a new continent for exploration. The subsequent finding that v-src is a tyrosine kinase run wild substantiated the theory that cancer can originate from an unregulated cellular . . . [Full Text of this Article]

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