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Previous Volume 347:526-527 August 15, 2002 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Patients with chronic obstructive pulmonary disease have exacerbations characterized by increased dyspnea, accompanied by increases in coughing, sputum production and purulence, and wheezing. Although most of these episodes are self-limited, they are associated with substantial decrements in the quality of life¹ and account for a large fraction of expenditures for the treatment of chronic obstructive pulmonary disease, since exacerbations are the most common cause of hospitalization among patients with this disease. The precise nature of these episodes is not well understood; their characteristics suggest that they are acute infections of the intrapulmonary airways, but this is extremely difficult to demonstrate . . . [Full Text of this Article]

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New Strains of Bacteria and Exacerbations of COPD
Kureishi A., Hirschmann J. V., Bresser P., van Alphen L., Lutter R., Sethi S., Murphy T. F., Anthonisen N. R.
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N Engl J Med 2002; 347:2077-2079, Dec 19, 2002. Correspondence

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