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Correspondence
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Volume 347:690-691 August 29, 2002 Number 9
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Diagnosis of Smallpox

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 by Breman, J. G.
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To the Editor: In Table 1 of their article, Breman and Henderson (April 25 issue)1 list secondary syphilis as a maculopapular eruption, noting that it has frequently been confused with smallpox. In general, it is more difficult to differentiate chickenpox from smallpox than it is to distinguish secondary syphilis from smallpox. Osler described the consequences of a misdiagnosis: "[S]ometimes it is not easy to distinguish between them. . . . It is stated that the . . . starting-point in Montreal of the epidemic of 1885, was regarded as varicella and not isolated. If so, the mistake . . . . . . [Full Text of this Article]




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