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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 348:1150-1158 March 20, 2003 Number 12
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Case 9-2003 — An 18-Year-Old Man with Back and Leg Pain and a Nondiagnostic Biopsy Specimen
Alison M. Friedmann, M.D., Esther Oliva, M.D., Anthony L. Zietman, M.D., and Suzanne L. Aquino, M.D.

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Presentation of Case

An 18-year-old man was admitted to the hospital because of back and leg pain and a nondiagnostic biopsy specimen from a paravertebral mass.

The patient had been well until eight months earlier, when the back pain began. Despite the use of ibuprofen and local application of ice, the pain increased, and three months before admission, pain developed in the right lower leg. A chiropractor obtained a radiograph of the spine, which revealed a compression fracture at the L3 vertebra. About one month before admission, a computed tomographic (CT) scan of the lumbosacral spine, obtained at another facility, confirmed the presence . . . [Full Text of this Article]

Differential Diagnosis

Nontraumatic Back and Leg Pain in a Healthy Young Adult

Differential Diagnosis of Anterior Mediastinal Mass

            Thymic Neoplasms

            Lymphomas

            Carcinomas

            Mesenchymal Tumors

            Germ-Cell Tumors

Clinical Diagnosis

Diagnostic Procedure

Clinical Diagnosis

Dr. Alison M. Friedmann's Diagnosis

Pathological Discussion

Anatomical Diagnosis


Source Information

From the Department of Pediatric Hematology/Oncology, Massachusetts General Hospital, and the Department of Pediatrics, Harvard Medical School (A.M.F.); and the Departments of Pathology (E.O.), Radiation Oncology (A.L.Z.), and Radiology (S.L.A.), Massachusetts General Hospital and Harvard Medical School — both in Boston.


Related Letters:

Case 9-2003: Mediastinal Germ-Cell Tumor
Cohen D., Weintrob N., Friedmann A. M., Oliva E.
Extract | Full Text | PDF  
N Engl J Med 2003; 348:2469-2470, Jun 12, 2003. Correspondence

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