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Volume 348:1491-1494 April 10, 2003 Number 15
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Effect of Dialysis Dose and Membrane Flux in Maintenance Hemodialysis

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by Himmelfarb, J.
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by Eknoyan, G.
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To the Editor: We are concerned about the conclusions of the report by Eknoyan et al. on the multimillion-dollar Hemodialysis (HEMO) Study (Dec. 19 issue)1 that support the continued use of the current practice guidelines in the United States, which recommend a value of at least 1.2 for the single-pool Kt/V (where K represents the rate of urea clearance by the dialyzer in milliliters per minute, t the duration in minutes of the treatment session, and V the volume of distribution of urea in the patient in milliliters). There is now overwhelming evidence that such a dose is too low, . . . [Full Text of this Article]



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