FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 348:1599 April 17, 2003 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Ghosh, S. PubMed Citation

To the Editor: In the study by Ghosh et al. (Jan. 2 issue),¹ a regimen of two infusions of natalizumab at a dose of 6 mg per kilogram of body weight was associated with higher remission rates than was placebo at several intervals, except at week 6 (the primary end point). The failure to demonstrate a difference may be due in part to chance and to the use of a small study sample. Randomization is supposed to ensure equal distribution of base-line characteristics that may confound a clinical trial. However, in this study, the randomization process assigned 63 patients to . . . [Full Text of this Article]

This article has been cited by other articles:

• Charo, I. F., Ransohoff, R. M. (2006). The Many Roles of Chemokines and Chemokine Receptors in Inflammation. NEJM 354: 610-621 [Full Text]  
• Segui, J., Gironella, M., Sans, M., Granell, S., Gil, F., Gimeno, M., Coronel, P., Pique, J. M., Panes, J. (2004). Superoxide dismutase ameliorates TNBS-induced colitis by reducing oxidative stress, adhesion molecule expression, and leukocyte recruitment into the inflamed intestine. J. Leukoc. Biol. 76: 537-544 [Abstract] [Full Text]  
• Mittelbrunn, M., Molina, A., Escribese, M. M., Yanez-Mo, M., Escudero, E., Ursa, A., Tejedor, R., Mampaso, F., Sanchez-Madrid, F. (2004). VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responses. Proc. Natl. Acad. Sci. USA 101: 11058-11063 [Abstract] [Full Text]