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Correspondence
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Volume 348:1920-1925 May 8, 2003 Number 19
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Smallpox and Smallpox Vaccination

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To the Editor: In the January 30 issue, a laudable attempt was made to come to grips with the many issues surrounding terrorist use of variola. An essential point remains unclear, however. How easily is variola transmitted? In the model of Bozzette et al.,1 no control measures are taken until 26 days after the initial infection, 11 days after the expected development of rash. Mack,2 however, argues persuasively that secondary spread takes place only after the characteristic rash is evident; thus, all infection takes place during those 11 days. Once the rash is evident, I presume that control procedures would . . . [Full Text of this Article]




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