The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Clinical Implications of Basic Research
PreviousPrevious
Volume 348:2138-2139 May 22, 2003 Number 21
NextNext

Genetic Medicine and Obesity
Timothy John Aitman, M.D., Ph.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-PubMed Citation
Almost all common diseases, such as coronary heart disease, diabetes, and obesity, are genetically complex traits. Although they appear to run in families, they have no clear pattern of inheritance and their clinical expression has been attributed to the interaction between multiple genes and the environment, but the genes have been very hard to identify.1 Since identification of the genes involved is a crucial step toward understanding the molecular pathogenesis of complex diseases, new methods are needed to accelerate this process. A study by Schadt and colleagues of obesity in mice may provide such an approach.2

Schadt and his colleagues2 . . . [Full Text of this Article]


Source Information

From the Physiological Genomics and Medicine Group, Medical Research Council Clinical Sciences Centre, Imperial College Faculty of Medicine, Hammersmith Hospital, London.



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.