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Previous Volume 348:2151 May 22, 2003 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In their thought-provoking article, Du et al. (Feb. 6 issue)¹ report a striking correlation between the level of angiopoietin-1 in the lung and the degree of pulmonary vascular resistance in patients with pulmonary hypertension. The fact that these patients had various types of disease makes these findings difficult to interpret, especially since the majority of patients had chronic thromboembolic pulmonary hypertension and underwent thromboendarterectomy.

In contrast to other types of pulmonary hypertension, increased pulmonary vascular resistance in chronic thromboembolic pulmonary hypertension is due mostly to the obliteration of proximal vessels. In fact, the absence of major involvement . . . [Full Text of this Article]

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