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Correspondence
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Volume 348:2256-2257 May 29, 2003 Number 22
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Human Growth Hormone and Aging

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by Vance, M. L.
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To the Editor: Vance's discussion of growth hormone (Feb. 27 issue)1 omits important reports in the literature. The combination of growth hormone and exercise (unlike exercise alone) has been shown to increase type II muscle fibers in the elderly2 — an important finding, since frailty and sarcopenia are predominantly related to the loss of type II fibers. There is no mention of the fact that decreased levels of insulin-like growth factor I have been reported to be associated with angina pectoris,3 myocardial infarction,4 and atherosclerosis,5 which are the leading causes of death in this country. The discussion also excludes a . . . [Full Text of this Article]



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