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Volume 348:2257-2259 May 29, 2003 Number 22
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Nephropathy Induced by Contrast Medium

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 by Aspelin, P.
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To the Editor: The article by Aspelin et al. (Feb. 6 issue)1 regarding the lower incidence of contrast-medium–induced nephropathy in patients with diabetes and a serum creatinine concentration of 1.5 to 3.5 mg per deciliter who were treated with iodixanol, as compared with those who received iohexol, is promising. The authors claim that a high ratio of urinary albumin to creatinine did not correlate with a high peak increase in the serum creatinine concentration. Although it is easier to use a single urinary albumin-to-creatinine ratio than a 24-hour urine collection to screen for proteinuria, this approach has its own limitations.2 . . . [Full Text of this Article]


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