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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 348:2443-2451 June 12, 2003 Number 24
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Case 18-2003 — A 15-Year-Old Girl with Pain in the Left Leg and Back, Pruritus, and Thoracic Lymphadenopathy
Leslie E. Lehmann, M.D., Sudha Anupindi, M.D., and Nancy Lee Harris, M.D.

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Presentation of Case

A 15-year-old girl was admitted to the hospital because of pain in the left leg and back, pruritus, thoracic lymphadenopathy, and multiple pulmonary nodules.

The patient had been well until 11 months earlier, when she began to be awakened during the night by pain in the left hip, which lasted an hour or two on each occasion. Several months later, pain developed in the lower back, and she ascribed it to competitive horseback riding. Five months before admission, she began to have bitemporal headaches, which were most severe in the afternoon and were sometimes accompanied by photophobia. Several months before . . . [Full Text of this Article]

Differential Diagnosis

Infections

Idiopathic Diseases

Neoplasms

            Acute Leukemia

            Malignant Tumors of Bone

            Lymphoid Neoplasms

            Hodgkin's Lymphoma

Diagnostic Procedure

Clinical Diagnosis

Dr. Leslie E. Lehmann's Diagnosis

Pathological Discussion

Anatomical Diagnosis


Source Information

From the Department of Medicine, Children's Hospital (L.E.L.); the Department of Medicine, Dana–Farber Cancer Institute (L.E.L.); the Departments of Radiology (S.A.) and Pathology (N.L.H.), Massachusetts General Hospital; and the Departments of Medicine (L.E.L.), Radiology (S.A.), and Pathology (N.L.H.), Harvard Medical School — all in Boston.




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