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A correction has been published: N Engl J Med 2003;349(6):620.

Review Article
Current Concepts
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Volume 348:2646-2655 June 26, 2003 Number 26
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Thyroiditis
Elizabeth N. Pearce, M.D., Alan P. Farwell, M.D., and Lewis E. Braverman, M.D.

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The term thyroiditis encompasses many relatively common thyroid disorders, which have been classified according to various schemes (Table 1). In this article we review the diagnosis and treatment of the different types of thyroiditis.

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Table 1. Terminology for Thyroiditis.

 
Mechanisms of Autoimmune Thyroid Destruction

Thyroid Autoimmunity

Hashimoto's thyroiditis, painless sporadic thyroiditis, and painless postpartum thyroiditis all have an autoimmune basis (Table 2). In Hashimoto's thyroiditis, the antithyroid immune response begins with activation of thyroid antigen–specific helper T cells. According to one theory, this activation results from infection with a virus that has a protein similar to a thyroid protein, although clear evidence for a viral . . . [Full Text of this Article]

Genetic Susceptibility

Environmental Factors

Clinical and Biochemical Changes in Thyroiditis

Thyrotoxicosis

Hypothyroidism

Types of Thyroiditis

Hashimoto's Thyroiditis

Painless Postpartum Thyroiditis

Painless Sporadic Thyroiditis

Painful Subacute Thyroiditis

Suppurative Thyroiditis

Drug-Induced Thyroiditis

            Amiodarone

            Lithium

            Interferon Alfa and Interleukin-2

Riedel's Thyroiditis


Source Information

From the Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, Boston University School of Medicine, Boston (E.N.P., L.E.B.); and the Division of Endocrinology, University of Massachusetts Medical Center, Worcester (A.P.F.).

Address reprint requests to Dr. Braverman at the Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, 88 E. Newton St., Evans 201, Boston, MA 02118, or at lewis.braverman@bmc.org.


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