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Correction to Kelsen and Obel, N Engl J Med 348(9):817 February 27, 2003.

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Volume 348:2689 June 26, 2003 Number 26
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Diffuse Cerebral Infarction after Cardiac Arrest

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by Kelsen, J.
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To the Editor: In the Images in Clinical Medicine entitled "Fatal Cerebral Hypoxemia after Cardiac Arrest" (Feb. 27 issue),1 the term "hypoxemia" is misused.2 How can hypoxemia be cerebral, when the term refers to oxygen levels in the blood? More important, hypoxemia is a distinct insult from ischemia,3,4 and controlled experiments in animal models have shown that pure hypoxemia without heart stoppage does not cause brain necrosis.5,6 A better title for the image would have been "Widespread Brain Necrosis after Cardiac Arrest." This title would not have perpetuated the myth that hypoxemia by itself causes necrotizing brain damage.


Roland N. . . . [Full Text of this Article]



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