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Previous Volume 348:252-254 January 16, 2003 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Immunologists have long been alert to the possibility that the immune system eliminates many cancers at an early stage and slows down the progress of others.¹ In recent years, the concept of immune surveillance against cancer has received support from experiments in mice. An increased incidence of spontaneous or methylcholanthrene-induced tumors was observed in mice lacking interferon-, interferon- receptors, or perforin and also in mice deficient in recombinase-activating gene 2, which have severe immunodeficiency.² Processes other than immune rejection of tumor cells may contribute to these results,³ but it is likely that in mice, the immune system can eliminate . . . [Full Text of this Article]

Source Information

From the Ludwig Institute for Cancer Research, Université de Louvain, Brussels, Belgium.

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