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Images in Clinical Medicine
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Volume 348:414 January 30, 2003 Number 5
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Progression of the Lesion at the Site of Inoculation after Smallpox Vaccination

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Photographs show the progression of a lesion from vaccination in a healthy, previously unvaccinated 23-year-old woman. Undiluted smallpox vaccine (Dryvax, Wyeth Laboratories) was introduced into the skin of the upper arm by scarification with 15 punctures from a bifurcated needle. Tender axillary lymphadenopathy developed bilaterally on day 6 and was more marked on the ipsilateral side. Erythema and induration were noted from the 8th day after vaccination through the 11th day and measured 10 cm in diameter. On day 9, an erythematous streak appeared, extending anteriorly toward the axilla. Two physicians who examined the patient on day 10 (oral temperature, . . . [Full Text of this Article]

 

Related Letters:

Smallpox Vaccination
Artenstein A. W., Rubins K., Relman D. A.
Extract | Full Text | PDF  
N Engl J Med 2003; 348:1925, May 8, 2003. Correspondence

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