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Volume 348:467-468 January 30, 2003 Number 5
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A Smallpox False Alarm

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To the Editor: We report a case in which a man presented with a papulovesicular rash with centrifugal distribution (Figure 1) that had been preceded by four days of headache, backache, fever, nausea, and vomiting. Because the rash started on the face, evolved slowly, and was in the same stage of development on any one part of the body, smallpox was considered in the differential diagnosis. Urgent consultation was obtained, and health departments and the Centers for Disease Control and Prevention (CDC) were contacted. Limited specimens sent to the hospital laboratory tested positive for varicella–zoster virus (VZV) IgG, . . . [Full Text of this Article]




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