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Previous Volume 348:551-553 February 6, 2003 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In this issue of the Journal, Aspelin et al.¹ report findings from a prospective, randomized, double-blind trial that compared iodixanol, a third-generation, iso-osmolar, dimeric, nonionic iodinated contrast agent, with iohexol, a low-osmolar, monomeric, nonionic contrast agent. The use of iodixanol resulted in significantly fewer nephrotoxic effects in high-risk patients undergoing arteriography than iohexol did — findings that are important because a beneficial effect of this iso-osmolar agent on renal function had not previously been conclusively demonstrated in a randomized study.

Before the late 1960s, all iodinated contrast agents used for radiologic imaging were ionic monomers with an ionizing carboxyl group . . . [Full Text of this Article]

Source Information

From the Department of Radiology, University of Texas Houston Medical School, Houston.

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