Nosocomial, or hospital-acquired, infections (more appropriatelycalled health careassociated infections) are today byfar the most common complications affecting hospitalized patients.Indeed, the Harvard Medical Practice Study II found that a singletype of nosocomial infection surgical-wound infection constituted the second-largest category of adverse events.1Long considered the greatest risk that the hospital environmentposes to patients,2 nosocomial infections abruptly became theprovince of public health officers at the time of a nationwideepidemic of hospital-based staphylococcal infections, in 1957and 1958.3 Since then, the study and control of nosocomial infectionshave been profoundly shaped by the discipline . . . [Full Text of this Article]
The Nature of Nosocomial Infections
Prevention of Nosocomial Infections
Surgical-Site Infections
Outbreaks in Hospitals
The Patient-Safety Movement
Is the NNIS System a Model for Infection-Control Programs?
Source Information
From the Department of Clinical Epidemiology and Infectious Diseases, LDS Hospital; and the Department of Internal Medicine, University of Utah School of Medicine both in Salt Lake City.
This article has been cited by other articles:
Mertz, D., Koller, M., Haller, P., Lampert, M. L., Plagge, H., Hug, B., Koch, G., Battegay, M., Fluckiger, U., Bassetti, S.
(2009). Outcomes of early switching from intravenous to oral antibiotics on medical wards. J Antimicrob Chemother
64: 188-199
[Abstract][Full Text]
Kritchevsky, S. B., Braun, B. I., Bush, A. J., Bozikis, M. R., Kusek, L., Burke, J. P., Wong, E. S., Jernigan, J., Davis, C. C., Simmons, B., for the TRAPE Study Group,
(2008). The Effect of a Quality Improvement Collaborative to Improve Antimicrobial Prophylaxis in Surgical Patients: A Randomized Trial. ANN INTERN MED
149: 472-480
[Abstract][Full Text]
Gurses, A P, Seidl, K L, Vaidya, V, Bochicchio, G, Harris, A D, Hebden, J, Xiao, Y
(2008). Systems ambiguity and guideline compliance: a qualitative study of how intensive care units follow evidence-based guidelines to reduce healthcare-associated infections. Qual Saf Health Care
17: 351-359
[Abstract][Full Text]
Graves, N., McGowan, J. E. Jr
(2008). Nosocomial Infection, the Deficit Reduction Act, and Incentives for Hospitals. JAMA
300: 1577-1579
[Full Text]
Ge, Y., Biek, D., Talbot, G. H., Sahm, D. F.
(2008). In Vitro Profiling of Ceftaroline against a Collection of Recent Bacterial Clinical Isolates from across the United States. Antimicrob. Agents Chemother.
52: 3398-3407
[Abstract][Full Text]
Cohen, E., Austin, J., Weinstein, M., Matlow, A., Redelmeier, D. A.
(2008). Care of Children Isolated for Infection Control: A Prospective Observational Cohort Study. Pediatrics
122: e411-e415
[Abstract][Full Text]
Bellamy, E.
(2008). An evaluation of patient satisfaction regarding the care and information provided by infection control nurses relating to MRSA. British Journal of Infection Control
9: 6-10
[Abstract]
Pronovost, P. J., Berenholtz, S. M., Goeschel, C. A.
(2008). Improving the Quality of Measurement and Evaluation in Quality Improvement Efforts. American Journal of Medical Quality
23: 143-146
Rosenberg, A. D., Wambold, D., Kraemer, L., Begley-Keyes, M., Zuckerman, S. L., Singh, N., Cohen, M. M., Bennett, M. V.
(2008). Ensuring Appropriate Timing of Antimicrobial Prophylaxis. JBJS
90: 226-232
[Abstract][Full Text]
Tourmousoglou, C. E., Yiannakopoulou, E. Ch., Kalapothaki, V., Bramis, J., Papadopoulos, J. St.
(2008). Adherence to guidelines for antibiotic prophylaxis in general surgery: a critical appraisal. J Antimicrob Chemother
61: 214-218
[Abstract][Full Text]
Berry, L. L., Bendapudi, N.
(2007). Health Care: A Fertile Field for Service Research. Journal of Service Research
10: 111-122
[Abstract]
Koopman, E., Nix, D. E., Erstad, B. L., Demeure, M. J., Hayes, M. M., Ruth, J. T., Matthias, K. R.
(2007). End-of-procedure cefazolin concentrations after administration for prevention of surgical-site infection. Am J Health Syst Pharm
64: 1927-1934
[Abstract][Full Text]
Stensballe, J., Tvede, M., Looms, D., Lippert, F. K., Dahl, B., Tonnesen, E., Rasmussen, L. S.
(2007). Infection Risk with Nitrofurazone-Impregnated Urinary Catheters in Trauma Patients: A Randomized Trial. ANN INTERN MED
147: 285-293
[Abstract][Full Text]
Seri, I.
(2007). Historical Perspectives: Perinatal Profiles: Childbed Fever and Ignac Fulop Semmelweis. NeoReviews
8: e235-e238
[Full Text]
Krein, S. L., Hofer, T. P., Kowalski, C. P., Olmsted, R. N., Kauffman, C. A., Forman, J. H., Banaszak-Holl, J., Saint, S.
(2007). Use of Central Venous Catheter-Related Bloodstream Infection Prevention Practices by US Hospitals. Mayo Clin Proc.
82: 672-678
[Abstract][Full Text]
Hugonnet, S., Villaveces, A., Pittet, D.
(2007). Nurse Staffing Level and Nosocomial Infections: Empirical Evaluation of the Case-Crossover and Case-Time-Control Designs. Am J Epidemiol
165: 1321-1327
[Abstract][Full Text]
Amarasingham, R., Pronovost, P. J., Diener-West, M., Goeschel, C., Dorman, T., Thiemann, D. R., Powe, N. R.
(2007). Measuring Clinical Information Technology in the ICU Setting: Application in a Quality Improvement Collaborative. J. Am. Med. Inform. Assoc.
14: 288-294
[Abstract][Full Text]
Giacometti, A., Cirioni, O., Riva, A., Kamysz, W., Silvestri, C., Nadolski, P., Della Vittoria, A., Lukasiak, J., Scalise, G.
(2007). In Vitro Activity of Aurein 1.2 Alone and in Combination with Antibiotics against Gram-Positive Nosocomial Cocci. Antimicrob. Agents Chemother.
51: 1494-1496
[Abstract][Full Text]
Marsh-Ng, M. L., Burney, D. P., Garcia, J.
(2007). Surveillance of Infections Associated With Intravenous Catheters in Dogs and Cats in an Intensive Care Unit. Journal of the American Animal Hospital Association
43: 13-20
[Abstract][Full Text]
Pronovost, P., Needham, D., Berenholtz, S., Sinopoli, D., Chu, H., Cosgrove, S., Sexton, B., Hyzy, R., Welsh, R., Roth, G., Bander, J., Kepros, J., Goeschel, C.
(2006). An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU. NEJM
355: 2725-2732
[Abstract][Full Text]
Cole, M.
(2006). Qualitative research: a challenging paradigm for infection control. British Journal of Infection Control
7: 25-29
[Abstract]
Peng, M. M., Kurtz, S., Johannes, R. S.
(2006). Adverse Outcomes From Hospital-Acquired Infection in Pennsylvania Cannot Be Attributed to Increased Risk on Admission. American Journal of Medical Quality
21: 17S-28S
[Abstract]
Walz, J. M., Paterson, C. A., Seligowski, J. M., Heard, S. O.
(2006). Surgical Site Infection Following Bowel Surgery: A Retrospective Analysis of 1446 Patients. Arch Surg
141: 1014-1018
[Abstract][Full Text]
Burkhardt, O., Brunner, M., Schmidt, S., Grant, M., Tang, Y., Derendorf, H.
(2006). Penetration of ertapenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers measured by in vivo microdialysis. J Antimicrob Chemother
58: 632-636
[Abstract][Full Text]
Murff, H J, Dittus, R S
(2006). Near misses and research subjects.. Qual Saf Health Care
15: 228-229
[Full Text]
Dubik, M., Barton, L.
(2006). Computer Bugs. AAP Grand Rounds
16: 22-23
[Full Text]
Tan, J A, Naik, V N, Lingard, L
(2006). Exploring obstacles to proper timing of prophylactic antibiotics for surgical site infections. Qual Saf Health Care
15: 32-38
[Abstract][Full Text]
Leverstein-van Hall, M. A., Blok, H. E. M., Paauw, A., Fluit, A. C., Troelstra, A., Mascini, E. M., Bonten, M. J. M., Verhoef, J.
(2006). Extensive Hospital-Wide Spread of a Multidrug-Resistant Enterobacter cloacae Clone, with Late Detection Due to a Variable Antibiogram and Frequent Patient Transfer. J. Clin. Microbiol.
44: 518-524
[Abstract][Full Text]
Odom-Forren, J., Hahn, E. J.
(2006). Mandatory Reporting of Health Care-Associated Infections: Kingdon's Multiple Streams Approach.. Policy Politics Nursing Practice
7: 64-72
The UK Neonatal Staffing Study Group,
(2005). Relationship between probable nosocomial bacteraemia and organisational and structural factors in UK neonatal intensive care units. Qual Saf Health Care
14: 264-269
[Abstract][Full Text]
GLICK, M.
(2005). Antibiotics: Is the end in sight?. Journal of the American Dental Association
136: 844-845
[Full Text]
Spear, S. J., Schmidhofer, M.
(2005). Ambiguity and Workarounds as Contributors to Medical Error. ANN INTERN MED
142: 627-630
[Abstract][Full Text]
Mohr, J., Peninger, M., Ostrosky-Zeichner, L.
(2005). Infection Control in Intensive Care Units. Journal of Pharmacy Practice
18: 84-90
[Abstract]
Best, M, Neuhauser, D
(2004). Ignaz Semmelweis and the birth of infection control. Qual Saf Health Care
13: 233-234
[Full Text]
Peterson, L. R., Dalhoff, A.
(2004). Towards targeted prescribing: will the cure for antimicrobial resistance be specific, directed therapy through improved diagnostic testing?. J Antimicrob Chemother
53: 902-905
[Abstract][Full Text]
Dulworth, S., Pyenson, B.
(2004). Healthcare-Associated Infections and Length of Hospital Stay in the Medicare Population. American Journal of Medical Quality
19: 121-127
[Abstract]
Safdar, N., Maki, D. G.
(2004). Quality of Care and Satisfaction Among Patients Isolated for Infection Control. JAMA
291: 420-421
[Full Text]
Stelfox, H. T., Bates, D. W., Redelmeier, D. A.
(2004). Quality of Care and Satisfaction Among Patients Isolated for Infection Control--Reply. JAMA
291: 421-422
[Full Text]
Trampuz, A., Widmer, A. F.
(2004). Hand Hygiene: A Frequently Missed Lifesaving Opportunity During Patient Care. Mayo Clin Proc.
79: 109-116
[Abstract]
Stelfox, H. T., Bates, D. W., Redelmeier, D. A.
(2003). Safety of Patients Isolated for Infection Control. JAMA
290: 1899-1905
[Abstract][Full Text]
Classen, D.
(2003). Medication Safety: Moving From Illusion to Reality. JAMA
289: 1154-1156
[Full Text]