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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
While obtaining a peripheral venous blood sample from a patient with the acquired immunodeficiency syndrome (AIDS), a 35-year-old phlebotomist is injured by a bloody 18-gauge needle attached to a syringe. The patient has been taking didanosine and stavudine for more than six months, but her quantitative plasma human immunodeficiency virus (HIV) RNA titer and CD4 T-lymphocyte count have not been measured for
The Clinical Problem
Strategies and Evidence
Risk of HIV Transmission
Benefits of Chemoprophylactic Treatment
Risks Associated with Chemoprophylactic Treatment
Antiretroviral-Drug Resistance
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Centers for Disease Control and Prevention, Atlanta.
Address reprint requests to Dr. Gerberding at the Centers for Disease Control and Prevention, Mailstop D14, 1600 Clifton Rd., Atlanta, GA 30333, or at jgerberding@cdc.gov.
Related Letters:
Occupational Exposure to HIV
Worthington M. G., Pino M., Bergeron E. K., Dedicoat M., Puro V., Gerberding J. L.
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Full Text |
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N Engl J Med 2003;
349:1091-1092, Sep 11, 2003.
Correspondence
This article has been cited by other articles:
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