In this issue of the Journal, Wainwright et al.1 provide datafrom a clinical trial in which 194 infants hospitalized withbronchiolitis were treated with inhaled epinephrine or placebo.In this age of commercial support for clinical trials, fundingis available only when commercial sponsors stand to make a profitfrom the manufacture of a drug. Thus, Wainwright et al. areto be congratulated for having tackled an important questionusing a multicenter, randomized, blinded clinical trial thatdoes not involve a new drug. The authors' findings overturnthe popular notion that treatment of bronchiolitis with inhaledepinephrine, as compared . . . [Full Text of this Article]
Source Information
From Harvard Medical School, Boston (M.E.B.W.); and the University of Manitoba, Winnipeg, Man., Canada (V.C.).
Related Letters:
Treatment of Bronchiolitis
Zwerdling R. G., O'Sullivan B. P., Wainwright C., Francis P., Wohl M. E., Chernick V.
Extract |
Full Text |
PDF
N Engl J Med 2003;
349:1384-1385, Oct 2, 2003.
Correspondence
This article has been cited by other articles:
Boogaard, R., Hulsmann, A. R., van Veen, L., Vaessen-Verberne, A. A. P. H., Yap, Y. N., Sprij, A. J., Brinkhorst, G., Sibbles, B., Hendriks, T., Feith, S. W. W., Lincke, C. R., Brandsma, A. E., Brand, P. L. P., Hop, W. C. J., de Hoog, M., Merkus, P. J. F. M.
(2007). Recombinant Human Deoxyribonuclease in Infants With Respiratory Syncytial Virus Bronchiolitis. Chest
131: 788-795
[Abstract][Full Text]
Gold, D. R., Fuhlbrigge, A. L.
(2006). Inhaled corticosteroids for young children with wheezing.. NEJM
354: 2058-2060
[Full Text]
Kellner, J. D
(2004). Review: commonly used pharmacological treatments for bronchiolitis in children do not seem to be effective. EDUCATION AND PRACTICE
89: ep79-ep79
[Full Text]
Kellner, J. D
(2004). Review: commonly used pharmacological treatments for bronchiolitis in children do not seem to be effective. Evid. Based Med.
9: 141-141
[Full Text]
Zwerdling, R. G., O'Sullivan, B. P., Wainwright, C., Francis, P., Wohl, M. E., Chernick, V.
(2003). Treatment of Bronchiolitis. NEJM
349: 1384-1385
[Full Text]
(2003). Treatment of Bronchiolitis: Answers at Last?. JWatch General
2003: 5-5
[Full Text]