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Correspondence
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Volume 349:96 July 3, 2003 Number 1
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"Silent" Strokes and Dementia

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To the Editor: Vermeer et al. (March 27 issue)1 demonstrate associations between "silent" (asymptomatic) stroke and recurrent stroke and dementia. The risk of large strokes was the highest, with nonsignificant trends toward an increased risk of small-vessel or white-matter lesions. Whether incident silent infarcts and incident symptomatic infarcts confer similar risks of recurrent symptomatic stroke and dementia is unclear. If an analogy to carotid disease holds, there may be different risks for silent strokes and for symptomatic strokes.

Although the accompanying editorial by Blass and Ratan2 raises important issues about risk-factor modification in patients with a silent stroke, information is . . . [Full Text of this Article]




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