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Images in Clinical Medicine
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Volume 349:968 September 4, 2003 Number 10
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The Harlequin Color Change

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On the third day of life, balloon dilatation of the pulmonary valve was performed in a full-term newborn with pulmonary atresia. Eight days later, asymptomatic, macular, blanchable erythema developed, involving areas of the head and neck and half of the trunk (Panel A), with sharp demarcation along the midline (Panel B). Over the course of a week, the color change fluctuated in both intensity and extent, demonstrating a migratory pattern that varied by the hour. Intravenous diphenhydramine and topical hydrocortisone had no benefit. The erythema gradually disappeared as the infant was weaned from prostaglandin E1 therapy; there were no sequelae. . . . [Full Text of this Article]

 



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