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Volume 349:999-1000 September 4, 2003 Number 10
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Lung-Volume–Reduction Surgery

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by National Emphysema Treatment Trial Research Group
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To the Editor: The report on the National Emphysema Treatment Trial (May 22 issue)1 states that in the subgroup of patients with predominantly upper-lobe disease and low base-line exercise capacity, lung-volume–reduction surgery, as compared with medical therapy, resulted in a significant improvement in exercise capacity and a lower risk of death. However, there were strikingly high proportions of subjects with missing data at 6, 12, and 24 months, especially in the medical-therapy group (Figure 3 of the article).

In our experience, follow-up according to the protocol is extremely difficult in such seriously ill subjects because of the frequent occurrence of . . . [Full Text of this Article]



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