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Previous Volume 349:1192-1193 September 18, 2003 Number 12 Next

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To the Editor: Various hematologic disorders, including plasma-cell dyscrasia,¹ are increasingly being diagnosed in patients with human immunodeficiency virus (HIV) infection. Monoclonal gammopathy of undetermined significance (MGUS), generally considered to be a disease of the elderly, affects up to 3 percent of persons 50 years of age or older.² Nevertheless, the presence of a monoclonal protein in HIV-positive persons is not a rare event.³ Since the standard care for MGUS is regular follow-up and monitoring for progression, patients in whom MGUS is the initial manifestation of HIV infection could miss out on the benefit of early antiretroviral therapy, should the . . . [Full Text of this Article]

Related Letters:

HIV Infection Masquerading as Monoclonal Gammopathy of Unknown Significance
Aslam A., Misbah S. A., Pantanowitz L., Lu C. M., Dezube B. J.
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N Engl J Med 2003; 349:2362-2363, Dec 11, 2003. Correspondence

This article has been cited by other articles:

• Aslam, A., Misbah, S. A., Pantanowitz, L., Lu, C. M., Dezube, B. J. (2003). HIV Infection Masquerading as Monoclonal Gammopathy of Unknown Significance. NEJM 349: 2362-2363 [Full Text]