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Volume 349:1290-1292 September 25, 2003 Number 13
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Leisure Activities and the Risk of Dementia

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 by Verghese, J.
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To the Editor: Verghese et al. (June 19 issue)1 report that participation in cognitive leisure activities reduces the risk of dementia in subjects older than 75 years of age.1 We reexamined this relation in the Leiden 85-plus Study, a prospective, population-based study of 599 subjects at least 85 years old.2 All the subjects were visited annually for measurements of global cognitive function, cognitive speed, and memory during a mean follow-up of 3.6 years. Because the number of cognitive leisure activities at base line was significantly lower in those with poor cognitive function and in those with depressive symptoms, we restricted . . . [Full Text of this Article]


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