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Previous Volume 349:1535-1542 October 16, 2003 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Dementia is a generic term used to designate chronically progressive brain disease that impairs intellect and behavior to the point where customary activities of daily living become compromised.^1,2 In some patients, specific abnormalities, such as a vitamin B₁₂ deficiency, normal pressure hydrocephalus, multiple strokes, paraneoplastic encephalitis, or human immunodeficiency virus infection, are identified as the underlying cause. In others, characteristic sensory or motor abnormalities indicate that the dementia is a component of a more extensive neurologic disease such as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, or multiple sclerosis. In the majority of patients with dementia, however, none of these . . . [Full Text of this Article]

Clinical Presentation and Diagnosis

Language in Primary Progressive Aphasia

Pathophysiology

Neuropathology

Nosology

Conclusions

Source Information

From the Cognitive Neurology and Alzheimer's Disease Center, Northwestern Cognitive Brain Mapping Group, Departments of Neurology and Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago.

Address reprint requests to Dr. Mesulam at Northwestern University Medical School, 320 E. Superior St., Chicago, IL 60611, or at mmesulam@northwestern.edu.

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