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Previous Volume 349:1592-1594 October 23, 2003 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The prescription of medications has long been the most frequent therapeutic intervention in medicine. In 2000 in the United States, 173 million people filled 2.2 billion outpatient prescriptions, accounting for $103 billion in expenditures. Because all medications have risks, the appropriate therapeutic use of pharmaceutical agents requires quantitative information on safety as well as efficacy.

In this issue of the Journal, a thoughtful investigation reported by Strom and colleagues (pages 1628–1635) shows that patients who have had a hypersensitivity reaction to sulfonamide antibiotics are no more likely to have a reaction to nonantibiotic sulfonamides than are patients who have had . . . [Full Text of this Article]

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From the Division of Pharmacoepidemiology, Department of Preventive Medicine, and the Geriatric Research, Education and Clinical Center, Nashville Veterans Affairs Medical Center, Nashville.

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