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Volume 349:1691-1692 October 30, 2003 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Primary hyperparathyroidism is a state of excess secretion of parathyroid hormone and hypercalcemia, often with skeletal and renal complications. The disease usually results from a single parathyroid adenoma. Less commonly, tumors occur in multiple parathyroid glands, and in these cases the disease may be familial. Familial primary hyperparathyroidism may occur in several genetically distinct disorders, including multiple endocrine neoplasia types 1 and 2A, the hyperparathyroidism–jaw tumor (HPT-JT) syndrome, and familial hypocalciuric hypercalcemia, or it can present as a solitary abnormality (as in familial isolated hyperparathyroidism).

(See Glossary.)

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Primary hyperparathyroidism occurs in virtually all patients with multiple endocrine neoplasia type . . . [Full Text of this Article]

Source Information

From the Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Md.

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