Despite advances in emergency medical systems and in techniquesof resuscitation, sudden death from cardiac arrest remains amajor public health problem. Most persons who have an out-of-hospitalcardiac arrest do not survive.1,2 Those who are resuscitatedmay have severe, long-term cognitive impairment and motor impairmentdue to delays before a stable rhythm could be restored. In the1970s, motivated by the death of a colleague, Drs. Michel Mirowskiand Morton Mower, and their colleagues, developed the conceptof an implantable device that could automatically monitor andanalyze cardiac rhythm and deliver defibrillating shocks whenit detected ventricular fibrillation.3,4 After . . . [Full Text of this Article]
Components and Function
Detection of Arrhythmia
Other Functions of Implantable Defibrillators
Clinical Trials
Secondary-Prevention Trials
Defibrillator Therapy plus Drug Therapy in Secondary Prevention
Primary-Prevention Trials
Cardiac Resynchronization and the Implantable CardioverterDefibrillator
Complications
Follow-up
Factors Affecting Use
Summary
Source Information
From the Electrophysiology Laboratory, Cardiovascular Division, Department of Medicine, University of Virginia Health System, Charlottesville.
Address reprint requests to Dr. DiMarco at the Cardiovascular Division, Department of Medicine, University of Virginia Health System, P.O. Box 800158, Charlottesville, VA 22908-0158, or at jdimarco@virginia.edu.
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