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Previous Volume 349:1872-1873 November 6, 2003 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the review article by Merlini and Bellotti (Aug. 7 issue),¹ familial Mediterranean fever was listed as one of the common periodic-fever syndromes that may lead to reactive (amyloid protein A, or AA) amyloidosis. However, there is no correlation between the frequency and severity of periodic febrile attacks and AA amyloidosis.² The serum level of amyloid protein A is not constantly elevated. Some patients with frequent periodic febrile attacks are spared from the development of amyloidosis, whereas in other patients there is very early amyloid deposition. The major effect of colchicine seems to be the prevention of . . . [Full Text of this Article]

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