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Previous Volume 349:109-111 July 10, 2003 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Thrombosis was identified as a complication of cancer by Trousseau in 1865, and the combination of the two conditions is still often called Trousseau's syndrome. Arterial and, more commonly, venous thrombosis is a frequent complication of cancer and sometimes a harbinger of occult cancer. Moreover, the use of new and aggressive therapy for cancer increases the risk of thrombosis.

There are many causes of thrombosis in cancer. Cancer itself is often the underlying mechanism. When cells of the monocyte or macrophage lineage interact with malignant cells, they release tumor necrosis factor, interleukin-1, and interleukin-6, causing endothelial damage and sloughing of . . . [Full Text of this Article]

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From the Dallas Thrombosis–Hemostasis Clinical Center, University of Texas Southwestern Medical School, Dallas.

Related Letters:

Dalteparin Compared with an Oral Anticoagulant for Thromboprophylaxis in Patients with Cancer
Blot E., Gutman F., Thannberger A., Hull J. H.K., Hull P. J., Kaufman J. L., Nader F., Lee A. Y.Y., Levine M. N., Gent M., Bick R. L.
Extract | Full Text | PDF  
N Engl J Med 2003; 349:1385-1387, Oct 2, 2003. Correspondence

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