Generations of trainees have been taught that monochorionictwin placentas are monozygotic. A report by Souter et al. inthis issue of the Journal (pages 154158) invalidatesthis simple rule by convincingly demonstrating the associationof a monochorionic placenta with dizygotic twins. A brief reviewof the current understanding of twin pregnancy may help to putthis new finding into perspective.
Dizygotic, or fraternal, twins develop from two separate fertilizedeggs, whereas monozygotic, or identical, twins are derived froma single fertilized egg that has divided to form separate embryos(see Figure). The rate of monozygotic twinning is relatively. . . [Full Text of this Article]
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From the Institute of Pathology, Case Western Reserve University, Cleveland.
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