|
|
|||
| |||||||||||||||||||||||||||||||||||||||||||||||
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A 22-year-old woman who wants to become pregnant has had no menses since she discontinued the use of an oral contraceptive one year ago, and recently, galactorrhea developed. She takes no medications and has had no headaches, visual loss, dyspareunia, or decreased libido. Physical examination shows no abnormalities, except for the bilateral breast discharge. A test for serum human chorionic gonadotropin is
The Clinical Problem
Clinical Presentation
Causes of Hyperprolactinemia
Strategies and Evidence
Diagnostic Studies
Therapy
Microadenomas
Macroadenomas
Hypogonadism
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Department of Internal Medicine, University of Iowa, Iowa City.
Address reprint requests to Dr. Schlechte at the Department of Internal Medicine, 157 MRF, University of Iowa Hospitals and Clinics, 200 Hawkins Dr., Iowa City, IA 52242, or at janet-schlechte@uiowa.edu.
Related Letters:
Prolactinomas
Friedman T. C., Couldwell W. T., Weiss M. H., Laws E. R. Jr., Hortin G. L., Colao A., Lombardi G., Schlechte J.
Extract |
Full Text |
PDF
N Engl J Med 2004;
350:1054-1057, Mar 4, 2004.
Correspondence
This article has been cited by other articles:
HOME | SUBSCRIBE | SEARCH | CURRENT ISSUE | PAST ISSUES | COLLECTIONS | PRIVACY | HELP | beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved. |