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Previous Volume 349:2078-2079 November 20, 2003 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We expand on the data presented by Hermine et al., who demonstrated the antitumor efficacy of interferon alfa in hepatitis C virus (HCV)–infected patients with marginal-zone lymphoma.¹ We report the details of anti-HCV therapy in the patient from whom we established a B lymphoma cell line that is persistently infected with HCV.² In culture, the line continuously produces HCV, which can infect primary human hepatocytes, peripheral-blood mononuclear cells, and Raji cells.

In 1995, this patient, a 66-year-old man, was found to have cryoglobulinemia, with elevated levels of rheumatoid factor and creatinine. Antibody to HCV was present; the . . . [Full Text of this Article]

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