In persons who are fasting, lipids circulate in the plasma asconstituents of lipoprotein particles that are defined on thebasis of their density as very-low-, intermediate-, low-, andhigh-density lipoproteins. The lipoproteins categorized as very-low,low, and intermediate density, although differing in the contentand composition of their lipid core, have in common 1 mol ofapolipoprotein B-100 per particle. Subclasses that have specialbiologic importance have been recognized, such as the small,dense low-density lipoprotein (LDL) particles, which have greateratherogenic potential than their large, buoyant counterparts.
In addition to LDL, the plasma contains particles, called Lp(a)lipoprotein, . . . [Full Text of this Article]
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From the Lipoprotein Study Unit, Department of Medicine, and the Department of Biochemistry and Molecular Biology, University of Chicago, Chicago.
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