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Volume 349:2089-2090 November 27, 2003 Number 22
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Lp(a) Lipoprotein — Coping with Heterogeneity
Angelo M. Scanu, M.D.

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 by Ariyo, A. A.
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In persons who are fasting, lipids circulate in the plasma as constituents of lipoprotein particles that are defined on the basis of their density as very-low-, intermediate-, low-, and high-density lipoproteins. The lipoproteins categorized as very-low, low, and intermediate density, although differing in the content and composition of their lipid core, have in common 1 mol of apolipoprotein B-100 per particle. Subclasses that have special biologic importance have been recognized, such as the small, dense low-density lipoprotein (LDL) particles, which have greater atherogenic potential than their large, buoyant counterparts.

In addition to LDL, the plasma contains particles, called Lp(a) lipoprotein, . . . [Full Text of this Article]


Source Information

From the Lipoprotein Study Unit, Department of Medicine, and the Department of Biochemistry and Molecular Biology, University of Chicago, Chicago.


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