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A 19-year-old woman had acute lymphocytic leukemia. While she was in her first remission, she underwent bone marrow transplantation. Three months later, she had an oral eruption consistent with lichen planus–like hyperkeratotic striae of the tongue, which is an indication of chronic graft-versus-host disease. The white coating on the tongue could not be rubbed off. Culture and microscopical examination of the scraped material did not show active candidiasis. As the graft-versus-host disease worsened, the skin, liver, and gastrointestinal system became involved. In conjunction with acute lichen planus, there were erythema and pseudomembranous ulcerations in the oral cavity, as well as . . . [Full Text of this Article] |
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