Many professional societies in the United States recommend screeningfor colorectal cancer in asymptomatic, average-risk adults,beginning at 50 years of age. Screening achieves two goals:the detection of early-stage nonmetastatic cancers that aresurgically curable and the identification and removal of benignadenomatous polyps, the precursor lesions of nearly all adenocarcinomas.Several approaches to screening are available, ranging fromthe least expensive and least invasive, fecal occult-blood testing,to the more costly and invasive procedures flexiblesigmoidoscopy, barium enema, and colonoscopy. Each of thesetests has inherent strengths and weaknesses related to cost,risk, sensitivity, specificity, and availability.1
From the Department of Radiology (M.M.M.) and the Division of Gastroenterology (J.T.L.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston.
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