It is ironic and instructive that in the age of cellular andmolecular biology, great advances in our understanding of thepathophysiology of cardiovascular disease continue to be madeby pathologists who perform meticulous and imaginative studies.The concept of stable and unstable atherosclerotic plaques andimplications for coronary thrombosis and myocardial infarctioncan be attributed to several great cardiovascular pathologistsduring the past century.
What characterizes an arterial plaque that is vulnerable torupture? What causes the vulnerable plaque to rupture? How canplaque rupture be prevented? These are critically importantquestions in cardiovascular medicine, because if the causes. . . [Full Text of this Article]
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From the University of Iowa Carver College of Medicine and Veterans Affairs Medical Center, Iowa City.
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