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A 35-year-old man with human immunodeficiency virus infection was admitted because of weight loss, fatigue, anorexia, and chronic, watery, nonbloody diarrhea. The workup for diarrhea revealed steatorrhea (110 g of fat per 24 hours). The patient had a history of chronic pancreatitis. A computed tomographic scan of the abdomen showed a cecal polypoid mass (arrow, Panel A). On colonoscopy, a 4-cm mass was seen at the cecum (Panel B). Examination of biopsy specimens of the mass showed proliferating spindle cells infiltrating the lamina propria, a finding consistent with the presence of Kaposi's sarcoma.
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